Live, have lived, or have traveled to parts of the country, such as the Ohio and Mississippi River valleys and the Southwest, that increase your risk of getting certain kinds of fungal infections.Have other medical conditions, including liver problems, low blood cell counts, diabetes, chronic lung disease, HIV, or a weak immune system.Have or have had any type of cancer, hepatitis B or C, shingles (herpes zoster), blood clots in the veins of your legs or lungs, diverticulitis (inflammation in parts of the large intestine), or ulcers in your stomach or intestines.Have had a heart attack, other heart problems, or stroke.Have TB or have been in close contact with someone with TB.- Burning when urinating or urinating more often than normal.
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- Warm, red, or painful skin or sores on your body.Are being treated for an infection, have an infection that won't go away or keeps coming back, or have symptoms of an infection, such as:.What should I tell my HCP BEFORE starting RINVOQ? See the Medication Guide or Consumer Brief Summary for a complete list of ingredients. Your HCP may stop your RINVOQ treatment for a period of time if needed because of changes in these blood test results.ĭo not take RINVOQ if you are allergic to upadacitinib or any of the ingredients in RINVOQ. Your HCP should do blood tests before you start taking RINVOQ and while you take it. Get medical help right away if you get stomach-area pain, fever, chills, nausea, or vomiting. This happens most often in people who take nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids.
If any of these symptoms occur during treatment with RINVOQ, stop taking RINVOQ and get emergency medical help right away. Symptoms such as rash (hives), trouble breathing, feeling faint or dizzy, or swelling of your lips, tongue, or throat, that may mean you are having an allergic reaction have been seen in people taking RINVOQ. Blood clots in the veins of the legs and lungs have happened more often in people who are 50 years and older and with at least 1 heart disease (CV) risk factor. This may be life-threatening and cause death. Blood clots in the veins of the legs or lungs and arteries can happen with RINVOQ. Increased risk of major cardiovascular (CV) events, such as heart attack, stroke, or death, in people 50 years and older who have at least 1 heart disease (CV) risk factor, especially if you are a current or past smoker.Wear protective clothing when you are in the sun and use sunscreen. Limit the amount of time you spend in sunlight.
Follow your HCP's advice about having your skin checked for skin cancer during treatment with RINVOQ. Current or past smokers are at higher risk of certain cancers, including lymphoma and lung cancer.
Lymphoma and other cancers, including skin cancers, can happen. RINVOQ may increase your risk of certain cancers.
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